Human Corin ELISA Kit

Cannot supply to this region.

SKU:: KOA0759
Additional Names:: activated protease fragment, ATC 2, ATC2, Atrial natriuretic peptide-converting enzyme, Atrial natriuteric peptide converting enzyme, Corin, Corin serine peptidase, CORIN_HUMAN, CRN, Heart specific serine proteinase, Heart specific serine proteinase ATC2, Heart-specific serine proteinase ATC2, Lrp 4, Lrp4, MGC119742, Pro ANP convertase, Pro ANP converting enzyme, Pro-ANP-converting enzyme, TMPRSS 10, TMPRSS10, Transmembrane protease serine 10|CORIN
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: S67-N1042
Species:: Human
Uniprot:: Q9Y5Q5
Synonyms:: ATC2;atrial natriuretic peptide-converting enzyme;Corin;CRN;heart-specific serine proteinase ATC2;Lrp4;PEE5;pro-ANP-convertase;pro-ANP-converting enzyme;TMPRSS10;transmembrane protease serine 10
Extra Details:: Atrial natriuretic peptide-converting enzyme, also called CRN or ATC2, is a protein that in humans is encoded by the CORIN gene. It is mapped to 4p12. This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. It has been found that Corin is the pro-ANP-converting enzyme and that Corin-mediated pro-ANP activation may play a role in regulating blood pressure. What's more, Corin and ANP are essential for physiologic changes at the maternal-fetal interface. This protein may also function as a pro-brain-type natriuretic peptide convertase. Corin gene mutations which cause Corin to impair activity might be an underlying mechanism in hypertension.

Shipping Conditions:: Blue Ice