Mouse Prostasin ELISA Kit

Cannot supply to this region.

SKU:: KOA0749
Additional Names:: 2410039E18Rik, AI313909, C79772, CAP1, Channel Activating Protease 1, mCAP1, Prostasin, Prostasin heavy chain, protease, serine, 8, Prss8, PRSS8_HUMAN, Serine protease 9|PRSS8
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Mouse
Immunogen:: Expression system for standard: NSO; Immunogen sequence: A30-Q289
Species:: Mouse
Uniprot:: Q9ESD1
Synonyms:: 2410039E18Rik;AI313909;C79772;CA;CAP1;channel activating protease 1;Channel-activating protease 1;f;fr;mCA;mCAP1;prostasin;serine protease 8
Extra Details:: Prostasin is a protein that in humans is encoded by the PRSS8 gene. It is a single-copy gene and mapped to 16p11.2. Prostasin is likely to be the more physiologically relevant protease. This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. Coexpression of Prostasin with either Xenopus or rat ENaC in Xenopus oocytes resulted in a 60% to 80% increase in amiloride-sensitive sodium currents, and that the addition of aprotinin, a serine protease inhibitor, completely prevented this activation. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.