Human Ficolin-3 ELISA Kit

Cannot supply to this region.

SKU:: KOA0743
Additional Names:: Collagen/fibrinogen domain containing lectin 3 p35, Collagen/fibrinogen domain containing protein 3, FCN 3, FCNH, Ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen), Ficolin (collagen/fibrinogen domain containing) 3, Ficolin 3, H ficolin, HAKA1, Hakata antigen, MGC22543|FCN3
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: Q24-R299
Species:: Human
Uniprot:: O75636
Synonyms:: collagen/fibrinogen domain-containing lectin 3 p35;collagen/fibrinogen domain-containing protein 3;FCNH;ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen);ficolin-3;H-ficolin;HAKA1;Hakata antigen
Extra Details:: Ficolin-3, also known as HAKA1, is a protein that in humans is encoded by the FCN3 gene. It is mapped to 1p36.11. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Ficolin-3 is expressed as a 35-kD protein that reacts with systemic lupus erythematosus sera. Ficolin-3 does not bind fibronectin(FN1), elastin(ELN), or zymosan, and the lectin activity of the Ficolin-3 is calcium independent. Homozygosity for the variant in the FCN3 gene results in a recessive complement deficiency syndrome.