Human CD320 - 8D6A ELISA Kit

Cannot supply to this region.

SKU:: KOA0740
Additional Names:: 8D6, 8D6 antigen, 8D6A, CD320, CD320 antigen, CD320_HUMAN, FDC-signaling molecule 8D6, FDC-SM-8D6, TCblR, Transcobalamin receptor|CD320
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: S36-Y229
Species:: Human
Uniprot:: Q9NPF0
Synonyms:: 8D6;8D6 antigen;8D6A;CD320 antigen;FDC-signaling molecule 8D6;FDC-SM-8D6;TCBLR;TCN2R;transcobalamin 2 receptor;transcobalamin receptor
Extra Details:: CD320(cluster of differentiation 320), also known as 8D6A or TCBLR, is a human gene. It is mapped to chromosome 19p13.2. This gene encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin(vitamin B12), and the expression of CD320 enhanced B-cell proliferation and immunoglobulin secretion. Mutations in this gene are associated with methylmalonic aciduria. It has been found that antagonists of the CD320 signaling pathway may counter the growth of follicular lymphomas or other tumors that metastasize to lymphoid follicles. CD320 is also a specific receptor for uptake of TCN2-bound cobalamin.