Mouse TNFRSF14 - HVEM ELISA Kit

Cannot supply to this region.

SKU:: KOA0720
Additional Names:: CD270, Herpes virus entry mediator A, Herpesvirus entry mediator A, HveA, TNFRSF14, TNR14_HUMAN, TR2, Tumor necrosis factor receptor superfamily member 14, Tumor necrosis factor receptor-like 3|TNFRSF14
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Mouse
Immunogen:: Expression system for standard: CHO; Immunogen sequence: Q29-V207
Species:: Mouse
Uniprot:: Q80WM9
Synonyms:: A;Atar;herpes virus entry mediator A;herpesvirus entry mediator A;Hv;Hve;HveA;Hvem;Tnfrs14;TR2;tumor necrosis factor receptor superfamily member 14;tumor necrosis factor receptor-like 2
Extra Details:: Tumor necrosis factor receptor superfamily member 14(TNFRSF14), also known as HVEM, is a protein that in humans is encoded by the TNFRSF14 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. It is mapped to 1p36.32. HVEM plays an important role in HSV pathogenesis because it enhanced the entry of several wildtype HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T cells. HVEM and BTLA which are form a bidirectional signaling pathway can regulate cell survival and inhibitory responses between interacting cells. HVEM as an important orchestrator of mucosal immunity integrates signals from innate lymphocytes to induce optimal epithelial Stat3 activation, which indicated that targeting HVEM with agonists could improve host defense.

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