Human soluble CD5 ELISA Kit

Cannot supply to this region.

SKU:: KOA0713
Additional Names:: CD 5, CD5, CD5 antigen (p56 62), CD5 antigen, CD5 molecule, CD5_HUMAN, LEU 1, LEU1, Ly12, LyA, Lymphocyte Antigen CD5, Lymphocyte antigen T1/Leu 1, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, OTTHUMP00000236973, p56 62, T cell surface glycoprotein CD5, T-cell surface glycoprotein CD5, T1|CD5
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: R25-N371
Species:: Human
Uniprot:: P06127
Synonyms:: CD5 antigen (p56-62);epididymis secretory sperm binding protein;LEU1;lymphocyte antigen T1/Leu-1;T-cell surface glycoprotein CD5;T1
Extra Details:: CD5, also known as T1 or LEU1, is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. It is mapped to 11q12.2. Although CD5 can be found on both T cells and B cells, T cells express higher levels of CD5 than B cells. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed. CD5 is upregulated on T cells upon strong activation. In the thymus, there is a correlation with CD5 expression and strength of the interaction of the T cell towards self-peptides. Nevertheless, CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli(such as bacterial proteins) and not by normal tissue proteins.

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