KOA0660
Mouse PCSK9 ELISA Kit
Cannot supply to this region.
- SKU:
- KOA0660
- Additional Names:
- Convertase subtilisin/kexin type 9 preproprotein, FH3, HCHOLA3, Hypercholesterolemia autosomal dominant 3, LDLCQ1, NARC 1, NARC-1, NARC1, Neural apoptosis regulated convertase 1, Neural apoptosis-regulated convertase 1, PC 9, PC9, PCSK 9, PCSK9, PCSK9_HUMAN, Proprotein convertase 9, Proprotein convertase PC9, Proprotein convertase subtilisin/kexin type 9, PSEC0052, Subtilisin/kexin like protease PC9, Subtilisin/kexin-like protease PC9|PCSK9
- Application:
- ELISA
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Reactivities:
- Mouse
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: S156Q-694
- Species:
- Mouse
- Uniprot:
- Q80W65
- Synonyms:
- AI415265;AI747682;convertase subtilisin;FH3;HCHOLA3;Na;NARC-1;Narc1;neural apoptosis regulated convertase 1;Neural apoptosis-regulated convertase 1;PC9;proprotein convertase 9;proprotein convertase PC9;proprotein convertase subtilisin/kexin type 9;subtilisin/kexin-like protease PC9
- Extra Details:
- Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A(EGF-A) domain of the low-density lipoprotein receptor(LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins(LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.
- Shipping Conditions:
- Blue Ice