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KOA0656

Mouse TNFRSF13B - TACI ELISA Kit

Cannot supply to this region.

SKU:
KOA0656
Additional Names:
CD267, TNFRSF13B, TR13B_HUMAN, Transmembrane activator and CAML interactor, Tumor necrosis factor receptor superfamily member 13B|TNFRSF13B
Application:
ELISA
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Reactivities:
Mouse
Immunogen:
Expression system for standard: NSO; Immunogen sequence: A2-C128
Species:
Mouse
Uniprot:
Q9ET35
Synonyms:
1200009E08Rik;Ta;Taci;transmembrane activator and calcium-modulating and cyclophilin ligand interactor;transmembrane activator and CAML interactor;tumor necrosis factor receptor superfamily member 13B
Extra Details:
Tumor necrosis factor receptor superfamily member 13B, also known as TNFRSF13B or more commonly as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. TACI controls T cell-independent B cell antibody responses, isotype switching, and B cell homeostasis. TACI is a lymphocyte-specific member of the tumor necrosis factor(TNF) receptor superfamily. It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand(CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. These proteins signal through TACI inducing activation of several transcription factors including NFAT, AP-1, and NF-kappa-B which then modulate cellular activities. Defects in the function of TACI can lead to immune system diseases.
Shipping Conditions:
Blue Ice