Mouse IL-15RA ELISA Kit

Cannot supply to this region.

SKU:: KOA0654
Additional Names:: AA690181, CD215, I15RA_HUMAN, IL 15R alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, IL15RA, Interleukin 15 receptor alpha, Interleukin 15 receptor subunit alpha, MGC104179, sIL-15 receptor subunit alpha, sIL-15R-alpha, sIL-15RA, Soluble interleukin 15 receptor subunit alpha, Soluble interleukin-15 receptor subunit alpha|IL15RA
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Mouse
Immunogen:: Expression system for standard: NSO; Immunogen sequence: G33-K205
Species:: Mouse
Uniprot:: Q60819
Synonyms:: AA690181;IL-15 receptor subunit alpha;IL-15R-alpha;IL-15RA;interleukin-15 receptor subunit alpha
Extra Details:: Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor which is encoded by the gene IL15RA in humans. The human IL15RA gene was mapped to chromosome 10p15-p14 by FISH and the mouse Il15ra gene was mapped to chromosome 2. The cytoplasmic domain of IL15R-alpha, like that of IL2R-alpha, was dispensable for mitogenic signaling, suggesting that the primary role of the alpha chains is to confer high-affinity binding. At high concentrations, IL15, like IL2, was able to signal through a complex of IL2R-beta and -gamma in the absence of the alpha subunit. The soluble receptor displayed high affinity for IL15 and inhibited both binding of IL15 to the membrane receptor and IL15-induced cell proliferation.