Human MICB ELISA Kit

Cannot supply to this region.

SKU:: KOA0593
Additional Names:: MHC class I chain related protein B, MHC class I like molecule PERB11.2 IMX, MHC class I mic B antigen, MHC class I polypeptide related sequence B, MHC class I polypeptide-related sequence B, MIC B, MIC-B, MICB, MICB_HUMAN, PERB11.2, Stress inducible class I homolog|MICB
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: A23-G298
Species:: Human
Uniprot:: Q29980
Synonyms:: MHC class I antigen-related protein B;MHC class I chain-related protein B;MHC class I mic-B antigen;MHC class I polypeptide-related sequence B;MHC class I-like molecule PERB11.2-IMX;PERB11.2;stress inducible class I homolog
Extra Details:: MHC class I polypeptide-related sequence B, also called MICB is a protein that in humans is encoded by the MICB gene. The MICB gene is mapped to 6p21.33. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer(NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. It seems to have no role in antigen presentation. This gene acts as a stress-induced self-antigen that is recognized by gamma delta T cells. It is the ligand for the KLRK1/NKG2D receptor and binds to KLRK1 leads to cell lysis.

Shipping Conditions:: Blue Ice