Human ADAMTS13 ELISA Kit

Cannot supply to this region.

SKU:: KOA0563
Additional Names:: A disintegrin and metalloproteinase with thrombospondin motifs 13, A disintegrin like and metalloprotease with thrombospondin type 1 motif 13, A disintegrin-like and metalloprotease (Reprolysin type) with thrombospondin type 1 motif 13, ADAM metallopeptidase with thrombospondin type 1 motif 13, ADAM TS, ADAMTS 13, ADAMTS13, ADAMTS13 protein, ATS13_HUMAN, TTP, Von Willebrand factor cleaving protease, vWF cleaving protease, vWFCP|ADAMTS13
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: CHO; Immunogen sequence: Q34-W688
Species:: Human
Uniprot:: Q76LX8
Synonyms:: A disintegrin and metalloproteinase with thrombospondin motifs 13;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13;ADAM-TS13;ADAMTS-13;C9orf8;von Willebrand factor-cleaving protease;vWF-cleaving protease;vWF-CP;VWFCP
Extra Details:: ADAMTS13 is a zinc-containing metalloprotease enzyme. The ADAMTS13 gene is mapped to chromosome 9q34 by genomic sequence analysis. It is reported that a metal-containing proteolytic enzyme (metalloprotease) in normal plasma cleaves the peptide bond between tyrosine at position 842 and methionine at position 843 in monomeric subunits of von Willebrand factor, thereby degrading the large multimers. And it is confirmed that the ADAMTS13 gene encodes the von Willebrand factor-cleaving protease (VWFCP). ADAMTS13 is secreted in blood and degrades large vWf multimers, decreasing their activity.

Shipping Conditions:: Blue Ice