Human Furin ELISA Kit

Cannot supply to this region.

SKU:: KOA0553
Additional Names:: Dibasic processing enzyme, Dibasic-processing enzyme, FES upstream region, FUR, FURIN, Furin membrane associated receptor protein, FURIN_HUMAN, PACE, Paired basic amino acid residue cleaving enzyme, Paired basic amino acid residue-cleaving enzyme, PCSK3, Proprotein convertase subtilisin/kexin type 3, SPC1|FURIN
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: D108-E715
Species:: Human
Uniprot:: P09958
Synonyms:: dibasic processing enzyme;Dibasic-processing enzyme;FES upstream region;FUR;furin;furin, membrane associated receptor protein;PACE;paired basic amino acid residue-cleaving enzyme;PCSK3;proprotein convertase subtilisin/kexin 3;proprotein convertase subtilisin/kexin type 3;SPC1;subtilisin-like proprotein convertase 1
Extra Details:: Furin (Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The FUR gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance.

Shipping Conditions:: Blue Ice