KOA0484
Human MIF ELISA Kit
Cannot supply to this region.
- SKU:
- KOA0484
- Additional Names:
- GIF, GLIF, Glycosylation inhibiting factor, L dopachrome isomerase, L dopachrome tautomerase, Macrophage migration inhibitory factor, Macrophage migration inhibitory factor (glycosylation inhibiting factor), MMIF, Phenylpyruvate tautomerase|MIF
- Application:
- ELISA
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Reactivities:
- Human
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: P2-A115
- Species:
- Human
- Uniprot:
- I4AY87
- Synonyms:
- epididymis secretory sperm binding protein;GIF;GLIF;L-dopachrome isomerase;L-dopachrome tautomerase;macrophage migration inhibitory factor;macrophage migration inhibitory factor (glycosylation-inhibiting factor);MMIF;phenylpyruvate tautomerase
- Extra Details:
- Macrophage migration inhibitory factor(MIF) is a protein which in humans is encoded by the MIF gene.1, 2 This gene is located to human chromosome 22q11.2.3 It is remarkably small; it has 3 exons separated by introns of only 189 and 95 bp, and covers less than 1 kb.4 This gene encodes a lymphokine that may be involved in cell-mediated immunity, immunoregulation, and inflammation.5 MIF plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein might form a complex in the cytosol near the peripheral plasma membrane, which may possibly indicate a role in integrin signaling pathways. MIF also plays a central role in the toxic response to endotoxemia and possibly septic shock. Macrophage migration inhibitory factor has been reported to interact with COP9 constitutive photomorphogenic homolog subunit 5, CD74, BNIPL, and CXCR4.
- Shipping Conditions:
- Blue Ice