Human DCR3 - TNFRSF6B ELISA Kit

Cannot supply to this region.

SKU:: KOA0440
Additional Names:: DcR3, Decoy Receptor 3, Decoy receptor for Fas ligand, DJ583P15.1.1, M68, M68E, OTTHUMP00000031583, TNF6B_HUMAN, TNFRSF6B, TR6, Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor receptor superfamily member 6b decoy, Tumor necrosis factor receptor superfamily member 6b decoy, UNQ186/PRO212|TNFRSF6B
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: sf21; Immunogen sequence: V24-H300
Species:: Human
Uniprot:: O95407
Synonyms:: DCR3;Decoy receptor 3;decoy receptor 3 variant 1;decoy receptor 3 variant 2;decoy receptor for Fas ligand;DJ583P15.1.1;M68;M68E;TR6;tumor necrosis factor receptor superfamily member 6B;tumor necrosis factor receptor superfamily, member 6b, decoy
Extra Details:: Decoy receptor 3 (Dcr3), also known as tumor necrosis factor receptor superfamily member 6B (TNFRSF6B), TR6 and M68, is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits Fas ligand-induced apoptosis. This gene belongs to the tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Overexpression of this gene has been noted in various tumors e.g. gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes.

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