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KOA0429

Human CXCL10 - IP-10 ELISA Kit

Cannot supply to this region.

SKU:
KOA0429
Additional Names:
10 kDa interferon gamma-induced protein, C7, Chemokine CXC motif ligand 10, Crg 2, CRG2, CXCL10, CXL10_HUMAN, Gamma IP10, gIP 10, GIP10, IFI10, INP 10, Interferon activated gene 10, Interferon gamma induced cell line, Interferon inducible cytokine IP10, IP 10, IP-10, MOB1, SCYB10, Small inducible cytokine B10, Small inducible cytokine B10 precursor, Small inducible cytokine subfamily B (Cys X Cys) member 10, Small inducible cytokine subfamily B CXC member 10, Small-inducible cytokine B10|CXCL10
Application:
ELISA
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Reactivities:
Human
Immunogen:
Expression system for standard: E.coli; Immunogen sequence: V22-P98
Species:
Human
Uniprot:
P02778
Synonyms:
10 kDa interferon gamma-induced protein;C-X-C motif chemokine 10;C7;crg-2;gamma IP10;gIP-10;IFI10;INP10;interferon-inducible cytokine IP-10;IP-10;mob-1;protein 10 from interferon (gamma)-induced cell line;SCYB10;small inducible cytokine subfamily B (Cys-X-Cys), member 10;small-inducible cytokine B10
Extra Details:
Chemokine(C-X-C motif) ligand 10(CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein(gamma-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. It is a potent inhibitor of angiogenesis in vivo. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. It is a RAS target gene and is overexpressed in the majority of colorectal cancers. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.
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