Rat CD80 - B7-1 ELISA Kit

Cannot supply to this region.

SKU:: KOA0412
Additional Names:: Activation B7-1 antigen, B7, BB1, CD80, CD80_HUMAN, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD82|CD80
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Rat
Immunogen:: Expression system for standard: NSO; Immunogen sequence: I39-Q248
Species:: Rat
Uniprot:: O35187
Synonyms:: B7-1;Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1);CD80 antigen;CD80-like;T-lymphocyte activation antigen CD80
Extra Details:: The protein CD80(Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7-1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain. The CD80 and CD86 genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.