Skip to content

View Spec Sheet

open_in_new
  1. Shop all
  2. ELISA Kits & Reagents

KOA0411

Mouse B7-1 - CD80 ELISA Kit

Cannot supply to this region.

SKU:
KOA0411
Additional Names:
Activation B7-1 antigen, B7, BB1, CD80, CD80_HUMAN, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD81|CD80
Application:
ELISA
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Reactivities:
Mouse
Immunogen:
Expression system for standard: NSO; Immunogen sequence: D37-K245
Species:
Mouse
Uniprot:
Q00609
Synonyms:
activation B7-1 antigen;B7 protein;B71;Cd28;Cd28l;Ly-5;Ly-53;Ly5;Ly53;MIC17;T-lymphocyte activation antigen CD80;TSA1
Extra Details:
The protein CD80(Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain. The CD80 and CD86(601020) genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. stated that B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4. The standard product used in this kit is recombinant B7-1, D37-K245, which is composed of two single chains acids with the dipolymer.
Shipping Conditions:
Blue Ice