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KOA0410

Human B7-1 - CD80 ELISA Kit

Cannot supply to this region.

SKU:
KOA0410
Additional Names:
Activation B7-1 antigen, B7, BB1, CD80, CD80_HUMAN, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80|CD80
Application:
ELISA
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Reactivities:
Human
Immunogen:
Expression system for standard: NSO; Immunogen sequence: V35-N242
Species:
Human
Uniprot:
P33681
Synonyms:
activation B7-1 antigen;B-lymphocyte activation antigen B7;B7;B7-1;B7.1;BB1;CD28LG;CD28LG1;CD80 antigen (CD28 antigen ligand 1, B7-1 antigen);costimulatory factor CD80;costimulatory molecule variant IgV-CD80;CTLA-4 counter-receptor B7.1;LAB7;T-lymphocyte activation antigen CD80
Extra Details:
The protein CD80(Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7-1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain. The CD80 and CD86 genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.
Shipping Conditions:
Blue Ice