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KOA0377

Mouse AXL ELISA Kit

Cannot supply to this region.

SKU:
KOA0377
Additional Names:
Adhesion related kinase, AI323647, Ark, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming gene, AXL transforming sequence/gene, JTK11, Oncogene AXL, Tyro7, Tyrosine protein kinase receptor UFO, UFO|AXL
Application:
ELISA
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Reactivities:
Mouse
Immunogen:
Expression system for standard: NSO; Immunogen sequence: H20-P443
Species:
Mouse
Uniprot:
Q00993
Synonyms:
A;adhesion-related kinase;AI323647;Ark;Tyr;Tyro7;tyrosine-protein kinase receptor UFO;Uf;Ufo;ufo oncogene homolog
Extra Details:
Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. It is in close vicinity to the bcl3 oncogene, which is at 19q13.1-q13.2. The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants.
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