KOA0371
Human CD105 ELISA Kit
Cannot supply to this region.
- SKU:
- KOA0371
- Additional Names:
- AI528660, AI662476, CD 105, CD105 antigen, Cell surface MJ7/18 antigen, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1, Osler Rendu Weber syndrome 1, OTTMUSP00000012838, OTTMUSP00000012839, RP11 228B15.2, RP23 17P12.4, S endoglin, Transmembrane glycoprotein|ENG
- Application:
- ELISA
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Reactivities:
- Human
- Immunogen:
- Expression system for standard: CHO; Immunogen sequence: E26-G586
- Species:
- Human
- Uniprot:
- P17813
- Synonyms:
- CD105 antigen;END;endoglin;HHT1;ORW1
- Extra Details:
- CD105, also called Endoglin, is a homodimeric membrane glycoprotein primarily associated with human vascular endothelium. It is also found on bone marrow proerythroblasts, activated monocytes, and lymphoblasts in childhood leukemia. Endoglin is a component of the transforming growth factor-beta(TGFB) receptor complex and binds TGFB1 with high affinity.1 CD105 gene is mapped to 9q34.1. The coding region of the gene contains 14 exons.2 The protein consists of a homodimer of 180 kDA with disulfide links. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. Furthermore, it also has a role in the balance of ALK1 and ALK5 signaling to regulate endothelial cell proliferation.3 Moreover, the elevated expression of endoglin in the surgically excised CNVMs suggested a persisting postmitotic activation in an advanced stage of neovascular tissue.4 The standard product used in this kit is extracellular part of recombinant huma.
- Shipping Conditions:
- Blue Ice