Mouse Amphiregulin - AR ELISA Kit

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SKU:: KOA0361
Additional Names:: A REG, AR|AREG, Colorectum cell derived growth factor, CRDGF, MGC13647, OTTHUMP00000219184, Schwannoma derived growth factor, SDGF|AREG
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Mouse
Immunogen:: Expression system for standard: E.coli; Immunogen sequence: V100-A248
Species:: Mouse
Uniprot:: P31955
Synonyms:: amphiregulin;AR;Mcub;schwannoma-derived growth factor;Sdg;Sdgf
Extra Details:: Amphiregulin, also known as AREG, is a protein that is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor family. This gene is mapped to mouse chromosome 5. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. Amphiregulin is related to to epidermal growth factor(EGF) and transforming growth factor alpha(TGF-alpha). This protein interacts with the epidermal growth factor receptor to promote the growth of normal epithelial cells. It has been found that transgene integration and subsequent expression of Amphiregulin in basal keratinocytes correlated with a psoriasis-like skin phenotype, and its expression was increased in parallel with typical Th2 cytokines. Amphiregulin is also an important paracrine mediator of estrogen function specifically required for puberty-induced ductal elongation but not for any earlier or later developmental stages, and it can enhance resistance to nematodes.

Shipping Conditions:: Blue Ice