Mouse CD30L ELISA Kit

Cannot supply to this region.

SKU:: KOA0348
Additional Names:: CD153 antigen, CD30 antigen ligand, CD30 L, CD30 ligand, CD30L, CD30LG, MGC138144, TNFSF8, Tumor necrosis factor (ligand) superfamily member 8, Tumor necrosis factor ligand superfamily member 8|TNFSF8
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Mouse
Immunogen:: Expression system for standard: NSO; Immunogen sequence: Q68-D239
Species:: Mouse
Uniprot:: P32972
Synonyms:: CD153;Cd30;CD30 ligand;CD30-L;Cd30l;CD30LG;Tnlg3a;tumor necrosis factor ligand 3a;tumor necrosis factor ligand superfamily member 8
Extra Details:: The human CD30L(CD153) gene is located at 9q33. It contains 4 exons and spans more than 17.1 kb. CD153 is expressed on the surface of B cells and this expression is upregulated upon CD154(CD40LG), IL4, and B-cell receptor engagement. In these cells, engagement of CD153 by T cell CD30 inhibits immunoglobulin class switch recognition as well as IgG, IgA, and IgE production, suggesting that this "reverse signaling" modulates the CD154-dependent switching of B cells into the pool producing IgG, IgA, and IgE. Additionally, recombinant human CD30L enhanced the proliferation of CD3 -activated T cells, but induced differential responses, including cell death, in several CD30-positive lymphoma-derived cell lines. The standard product used in this kit is recombinant mouse CD30L with the molecular mass of 30-45KDa.