Mouse TNFR2 ELISA Kit

Cannot supply to this region.

SKU:: KOA0323
Additional Names:: CD120b, Etanercept, p75, p80 TNF alpha receptor, TBP2, TBPII, TNF R2, TNFBR, TNFR-II, TNFR2, TNFRII, Tumor necrosis factor binding protein 2, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor superfamily member 1b, membrane form, Tumor necrosis factor receptor type II|TNFRSF1B
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Mouse
Immunogen:: Expression system for standard: NSO; Immunogen sequence: V23-G258
Species:: Mouse
Uniprot:: P25119
Synonyms:: CD120b;p7;p75;p75 TNFR;p80 TNF-alpha receptor;TN;Tnf;TNF receptor beta chain;TNF-;TNF-a;TNF-alphaR2;TNF-R;TNF-R-II;TNF-R2;TNF-R75;TNF-RII;TNFal;TNFalpha-R2;TNFBR;TNFR;Tnfr-1;TNFR-II;Tnfr2;TNFR80;TNFRII;tumor necrosis factor receptor 2;tumor necrosis factor receptor superfamily member 1B;tumor necrosis factor receptor type II
Extra Details:: Tumor necrosis factor receptor 2(TNFR2) is one of receptors of TNF. TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors(TNFRs), TNFR1 and TNFR2. The genes for TNFR1, a 55-kDa protein, and TNFR2, a 70-kDa protein, have been mapped to human chromosomes 12(12pter-cen) and 1(1pter-p32), respectively. TNFR2 was induced on glomerular endothelial cells of nephritic kidneys, and TNFR2 expression on intrinsic cells, but not leukocytes, was essential for glomerulonephritis and glomerular complement deposition. TNFR1 promotes systemic immune responses and renal T cell death, while intrinsic cell TNFR2 plays a critical role in complement-dependent tissue injury. Therefore, therapeutic blockade specifically of TNFR2 may be a promising strategy in the treatment of immune-mediated glomerulonephritis.

Shipping Conditions:: Blue Ice