Human TGF beta 1 ELISA Kit

Cannot supply to this region.

SKU:: KOA0307
Additional Names:: Camurati-Engelmann disease, CED, DPD1, LAP, Latency-associated peptide, TGF beta 1 protein, TGF-beta-1, TGFB, tgfb1, TGFB1_HUMAN, TGFbeta, Transforming growth factor beta 1|TGFB1
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Bovine, Canine, Human, Rabbit
Immunogen:: Expression system for standard: CHO; Immunogen sequence: A279-S390
Species:: Human
Uniprot:: P01137
Synonyms:: CED;DPD1;IBDIMDE;LAP;latency-associated peptide;prepro-transforming growth factor beta-1;TGF-beta-1;TGF-beta1;TGFB;TGFbeta;transforming growth factor beta-1 proprotein;transforming growth factor beta1
Extra Details:: Transforming growth factor-beta1 (TGF-beta1) is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGF-beta and essentially all of them have specific receptors for this peptide. TGF-beta regulates the actions of many other peptide growth factors and determines a positive or negative direction of their effects. TGF-beta1 is known for its potent and diverse biological effects, including immune regulation, and cell growth and differentiation. TGF-beta1 is also an important mediator of bone remodeling. TGF-beta1, a potent keratinocyte growth inhibitor, has been shown to be overexpressed in keratinocytes in certain inflammatory skin diseases and has been thought to counteract the effects of other growth factors at the site of inflammation. TGF-beta1, a multifunctional cytokine with fibrogenic properties, has been implicated in the pathogenesis of the vascular and target organ complications of hypertension. TGF-beta1 may also regulate blood pressure via stimulation of endothelin-1 and/or renin secretion. TGF-beta1 is secreted as a latent form, which consists of its mature form and a latency-associated peptide (beta1-LAP) in either the presence or the absence of additional latent TGF-beta1-binding protein. The standard product used in this kit is recombinant TGF beta1 with the molecular mass of 25KDa.

Shipping Conditions:: Blue Ice