Human SCF ELISA Kit

Cannot supply to this region.

SKU:: KOA0303
Additional Names:: C kit ligand, Ckit ligand, Kit ligand, Kitl, KITLG, KL 1, KL1, Mast cell growth factor, MGF, SF, SHEP7, Steel factor, Stem cell factor, Stem cell factor precursor|KITLG
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: E.coli; Immunogen sequence: E26-A190
Species:: Human
Uniprot:: P21583
Synonyms:: c-Kit ligand;DCUA;DFNA69;familial progressive hyperpigmentation 2;FPH2;FPHH;kit ligand;Kitl;KL-1;mast cell growth factor;MGF;SCF;SF;SHEP7;SLF;steel factor;stem cell factor
Extra Details:: Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). It is mapped to 12q21.32. SCF was primarily expressed by perivascular cells throughout the bone marrow, and it plays a role in the regulation of HSCs in the stem cell niche in the bone marrow. SCF can exist both as a transmembrane protein and a soluble protein. This gene plays an important role in the hematopoiesis during embryonic development. During development, the presence of the SCF also plays an important role in the localization of melanocytes, cells that produce melanin and control pigmentation. In addition to it, SCF can promote mast cell adhesion, migration, proliferation, and survival. It also promotes the release of histamine and tryptase, which are involved in the allergic response.