KOA0272
Human MMP-8 ELISA Kit
Cannot supply to this region.
- SKU:
- KOA0272
- Additional Names:
- BB138268, CLG 1, CLG1, Collagenase 1, Collagenase 1 neutrophil, HNC, Matrix metallopeptidase 8, Matrix metalloproteinase 8 (neutrophil collagenase), Matrix metalloproteinase-8, MMP 8, MMP-8, Mmp8, MMP8_HUMAN, Neutrophil collagenase, PMNL CL, PMNL collagenase, PMNL-CL|MMP8
- Application:
- ELISA
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Reactivities:
- Human
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: F21-G467
- Species:
- Human
- Uniprot:
- P22894
- Synonyms:
- CLG1;collagenase 2;HNC;matrix metalloproteinase 8 (neutrophil collagenase);matrix metalloproteinase-8;MMP-8;neutrophil collagenase;PMN leukocyte collagenase;PMNL collagenase;PMNL-CL
- Extra Details:
- Matrix metalloproteinase 8(MMP8) also called neutrophil collagenase. Neutrophil collagenase, a member of the family of matrix metalloproteinases, is distinct from the collagenase of skin fibroblasts and synovial cells in substrate specificity and immunologic cross reactivity. MMP8, an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. The human neutrophil collagenase(HNC) cDNA clone has been sequenced and shown to encode a 467-residue protein. Neutrophil collagenase has been found to possess 57% identity with the deduced protein sequence for fibroblast collagenase with 72% chemical similarity. Certain regions of the molecule, including the putative zinc-binding region, are highly conserved. When compared with the published sequence for fibroblast collagenase, neutrophil collagenase contains four additional sites for glycosylation. The standard product used in this kit is natural, isolating from human MMP-8. The detected MMP-8 includes zymogen and active enzyme.
- Shipping Conditions:
- Blue Ice