Human IL-11 ELISA Kit

Cannot supply to this region.

SKU:: KOA0232
Additional Names:: Adipogenesis inhibitory factor, AGIF, IL 11, IL-11, Il11, IL11_HUMAN, Interleukin 11, Interleukin-11, Interleukin11, Oprelvekin|IL11
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: E.coli; Immunogen sequence: P22-L199
Species:: Human
Uniprot:: P20809
Synonyms:: adipogenesis inhibitory factor;AGIF;IL-11;interleukin-11;oprelvekin
Extra Details:: Interleukin 11(IL-11) is a protein that in humans is encoded by the IL11 gene. The protein encoded by this gene is a member of the gp130 family of cytokines. This gene is mapped to 19q13.42. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. What's more, IL-11 can stimulate the growth of certain lymphocytes and it has functions in many other tissues, including the brain, gut, testis and bone. In transgenic mice, overexpression of the human IL11 gene resulted in the stimulation of bone formation to increase cortical thickness and strength of long bones.