Mouse FAS ELISA Kit

Cannot supply to this region.

SKU:: KOA0164
Additional Names:: ALPS1A, APO 1, APO 1 cell surface antigen, Apo-1 antigen, APO1, Apo1 antigen, Apoptosis antigen 1, Apoptosis mediating surface antigen FAS, Apoptosis-mediating surface antigen FAS, APT1, CD95, CD95 antigen, Fas, Fas AMA, Fas antigen, FAS1, FASLG receptor, FASTM, TNF receptor superfamily member 6, TNFRSF6, TNR6_HUMAN, Tumor necrosis factor receptor superfamily member 6|FAS
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Mouse
Immunogen:: Expression system for standard: sf21; Immunogen sequence: Q22-R169
Species:: Mouse
Uniprot:: Q8C350
Synonyms:: AI196731;AP;apo-1 antigen;APO1;apoptosis-mediating surface antigen FAS;APT1;CD95;Fas (TNF receptor superfamily member);Fas antigen;FASLG receptor;lpr;lymphoproliferation;TNF;Tnfr;TNFR6;Tnfrsf6;tumor necrosis factor receptor superfamily member 6
Extra Details:: Fas, also known as APO-1, CD95 and TNFRSF6, is a member of the nerve growth factor(NGF)/tumour necrosis factor(TNF) receptor superfamily and mediates apoptosis. The nucleotide sequence of the cDNAs reveals that the molecule coding for the Fas antigen determinant is a 419 amino acid polypeptide with a single transmembrane domain. The extracellular domain is rich in cysteine residue, and shows a similarity to that of human tumor necrosis factor receptors, human nerve growth factor receptor, and human B cell antigen CD40. The APO-1 antigen as defined by the mouse monoclonal antibody anti-APO-1 is previously found to be expressed on the cell surface of activated human T and B lymphocytes and a variety of malignant human lymphoid cell lines. The APO-1 antigen is found to be a membrane glycoprotein of 48-kDa. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. Fas can play a role as an inducer of both neurite growth in vitro and accelerates recovery after nerve injury in vivo.

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