612-401-E42
Tau phospho S416 Antibody
Cannot supply to this region.
- SKU:
- 612-401-E42
- Additional Names:
- Mapt|Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau
- Application:
- IHC, WB
- Physical State:
- Liquid
- Species Reactivity:
- Rat
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- Immunogen:
- Anti-Tau pS416 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser416 of the Tau protein.
- Formulation:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Uniprot:
- P19332
- Synonyms:
- 1700003M02Rik;AU024269;cilia- and flagella-associated protein 206;Neurofibrillary tangle protein;Paired helical filament-tau;UPF0704 protein C6orf165 homolog
- Extra Details:
- Tau pS416 Antibody detects Tau, which s a key microtubule-associated protein that plays an important role in the formation of microtubules in axons. Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing. Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer's disease (AD), Pick's disease and progressive supranuclear palsy. It has been well documented that hyperphosphorylated tau is a major component of paired helical filaments in AD brain. Serine 416 has been demonstrated to be a major phosphorylation site in vitro by CaM kinase II. Anti-Tau pS416 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
- Shipping Conditions:
- Dry Ice