PAK 1/2/3 phospho T402 Antibody

Cannot supply to this region.

SKU:: 612-401-E05
Additional Names:: Pak1/2/3|Serine/threonine-protein kinase PAK 1, Alpha-PAK, Protein kinase MUK2, p21-activated kinase 1, p68-PAK
Application:: WB
Physical State:: Liquid
Species Reactivity:: Rat
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Rat
Buffer:: 0.01 M HEPES, 0.15 M Sodium Chloride
Immunogen:: Anti-PAK 1/2/3 pT402 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Thr402.
Formulation:: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Uniprot:: P35465
Synonyms:: alpha-PAK;p21 (CDKN1A)-activated kinase 1;p21 protein (Cdc42/Rac)-activated kinase 1;p21-activated kinase 1;p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related);p68-PAK;PAK-1;protein kinase MUK2;serine/threonine-protein kinase PAK 1
Extra Details:: PAK 1/2/3 pT402 Antibody detects PAK 1/2/3 pT402 proteins. In mammals, there are several identified isoforms of p21-activated protein kinases or PAKs: A Alpha-PAK (also known as PAK-1) and B Beta-PAK (also known as PAK-3) are mostly brain-specific, while -PAK (also known as PAK-2) is expressed ubiquitously. Mutations of the gene coding for PAK-3 are associated with X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus. PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death. Autophosphorylation of Thr402 in the protein has been found to be essential for activation of PAK. Anti-PAK 1/2/3 pT402 Antibody is ideal for investigators involved in Neuroscience and Apoptosis research.

Shipping Conditions:: Dry Ice