612-401-D92
NMDA R2B phospho Y1252 Antibody
Cannot supply to this region.
- SKU:
- 612-401-D92
- Additional Names:
- Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B, Grin2b|Grin2b
- Application:
- IHC, WB
- Physical State:
- Liquid
- Species Reactivity:
- Rat
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- Immunogen:
- Anti-NMDA R2B pY1252 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1252.
- Formulation:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Uniprot:
- Q00960
- Synonyms:
- GluN2B;glutamate [NMDA] receptor subunit epsilon-2;glutamate receptor ionotropic, NMDA 2B;glutamate receptor, ionotropic, N-methyl D-aspartate 2B;glutamate receptor, ionotropic, NMDA2B;N-methyl D-aspartate receptor subtype 2B;NMDAR2B;NR2B
- Extra Details:
- NMDA R2B pY1252 Antibody detects NMDA R2B protein. The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Phosphorylation of Tyr1252 is thought to potentiate NMDA receptor-dependent influx of calcium. Anti-NMDA R2B pY1252 Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research.
- Shipping Conditions:
- Dry Ice