NMDA R2A Antibody

Cannot supply to this region.

SKU:: 612-401-D89
Additional Names:: Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, Grin2a|Grin2a
Application:: IHC, WB, IF
Physical State:: Liquid
Species Reactivity:: Rat
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Rat
Buffer:: 0.01 M HEPES, 0.15 M Sodium Chloride
Immunogen:: Anti-NMDA R2A Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the N-terminal region of the NR2A subunit.
Formulation:: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Uniprot:: Q00959
Synonyms:: GluN2A;glutamate [NMDA] receptor subunit epsilon-1;glutamate receptor ionotropic, NMDA 2A;glutamate receptor, ionotropic, N-methyl D-aspartate 2A;N-methyl D-aspartate receptor subtype 2A;N-methyl-D-aspartate receptor subunit 2A;NMDAR2A;NR2A
Extra Details:: NMDA R2A Antibody detects NMDA R2A protein. The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and A Alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Anti-NMDA R2A Antibody is ideal for investigators involved in Neuroscience, Cell Signaling, and Signal Transduction research.

Shipping Conditions:: Dry Ice