612-401-D24
DARPP-32 Antibody
Cannot supply to this region.
- SKU:
- 612-401-D24
- Additional Names:
- Ppp1r1b|Protein phosphatase 1 regulatory subunit 1B, Dopamine- and cAMP-regulated neuronal phosphoprotein
- Application:
- ELISA, IHC, WB
- Physical State:
- Liquid
- Species Reactivity:
- Rat
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Rat
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- Immunogen:
- Anti-DARPP-32 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.
- Formulation:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Uniprot:
- Q6J4I0
- Synonyms:
- Darpp-32;Darpp32;dopamine- and cAMP-regulated neuronal phosphoprotein;dopamine- and cAMP-regulated phosphoprotein DARPP-32;neuronal phosphoprotein DARPP-32;protein phosphatase 1 regulatory subunit 1B
- Extra Details:
- DARPP-32 Antibody detects DARPP-32 which is a dopamine (DA) and cAMP-regulated ~32k phosphoprotein that is associated with dopaminoceptive neurons. The protein inhibits protein phosphatase I when it is phosphorylated on Thr34. In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA. Phosphorylation of DARPP-32 is thought to play a critical role in the regulation of dopaminergic neurotransmission. In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac®. Anti-DARPP-32 Antibody is ideal for investigators involved in Neuroscience and Cell Signaling Research.
- Shipping Conditions:
- Dry Ice