600-901-G75
AP2M1 Antibody
Cannot supply to this region.
- SKU:
- 600-901-G75
- Additional Names:
- AP2M1|CLAPM1, KIAA0109
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Chicken/Avian
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- AP2M1 Antibody was produced in chicken by repeated immunizations with a peptide near the c-terminus of human AP2M1.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- Q96CW1
- Synonyms:
- adaptin-mu2;adaptor protein complex AP-2 subunit mu;adaptor related protein complex 2 mu 1 subunit;adaptor-related protein complex 2 subunit mu;AP-2 complex subunit mu;AP-2 mu 2 chain;AP-2 mu chain;AP50;CLAPM1;clathrin adaptor complex AP2, mu subunit;clathrin assembly protein complex 2 medium chain;clathrin assembly protein complex 2 mu medium chain;clathrin coat adaptor protein AP50;clathrin coat assembly protein AP50;clathrin coat-associated protein AP50;clathrin-associated/assembly/adaptor protein, medium 1;HA2 50 kDA subunit;MRD60;mu2;plasma membrane adaptor AP-2 50 kDa protein;plasma membrane adaptor AP-2 50kDA protein
- Extra Details:
- AP2M1 antibody detects human AP2M1. The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist. Anti-AP2M1 antibodies are ideal for investigators involved in infectious disease and enzyme research.
- Shipping Conditions:
- Dry Ice