600-401-Y33
APC3 Antibody
Cannot supply to this region.
- SKU:
- 600-401-Y33
- Additional Names:
- APC3 Antibody, APC3, HNUC, NUC2, ANAPC3, CDC27Hs, D0S1430E, D17S978E, Cell division cycle protein 27 homolog, Anaphase-promoting complex subunit 3, APC3|CDC27
- Application:
- ELISA, IHC, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-APC3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the C-terminus of human APC3.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P30260
- Synonyms:
- ANAPC3;anaphase promoting complex subunit 3;Anaphase-promoting complex subunit 3;anaphase-promoting complex, protein 3;APC3;CDC27 homolog;CDC27Hs;cell division cycle 27 homolog;cell division cycle protein 27 homolog;D0S1430E;D0S1430E, D17S978E;D17S978E;H-NUC;HNUC;NUC2;nuc2 homolog
- Extra Details:
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC3, also known as CDC27, a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), is a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. APC3 contains a tetratricopeptide repeat (TPR) region and interacts with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1.
- Shipping Conditions:
- Dry Ice