APBA1 Antibody

Cannot supply to this region.

SKU:: 600-401-Y29
Additional Names:: APBA1|APBA1 Antibody, X11, X11A, LIN10, MINT1, D9S411E, X11ALPHA, X11, Amyloid beta A4 precursor protein-binding family A member 1, Adapter protein X11alpha, Mint-1
Application:: ELISA, WB, IF
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
Immunogen:: Anti-APBA1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the N-terminus of human APBA1.
Formulation:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Uniprot:: Q02410
Synonyms:: adapter protein X11alpha;adaptor protein X11alpha;amyloid beta (A4) precursor protein-binding, family A, member 1 (X11);amyloid-beta A4 precursor protein-binding family A member 1;D9S411E;LIN10;mint-1;MINT1;neuron-specific X11 protein;neuronal munc18-1-interacting protein 1;phosphotyrosine-binding/-interacting domain (PTB)-bearing protein;X11;X11A;X11ALPHA
Extra Details:: The Amyloid beta 4 (A4) precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family and a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). APBA1 stabilizes APP and inhibits production of proteolytic APP fragments including the Ab peptide that is deposited in the brains of Alzheimer's disease patients. It is thought to be involved in signal transduction processes and is a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. APBA1 can also bind to CASK, a multidomain scaffolding protein involved in brain development and synapse formation.

Shipping Conditions:: Dry Ice