600-401-X44
PML Antibody
Cannot supply to this region.
- SKU:
- 600-401-X44
- Additional Names:
- PML|Protein PML Promyelocytic leukemia protein, RING finger protein 71, Tripartite motif-containing protein 19, MYL, PP8675, RNF71, TRIM19
- Application:
- ELISA, WB
- Concentration:
- 0.14 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-PML Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides from human PML.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P29590
- Synonyms:
- E3 SUMO-protein ligase PML;MYL;PML/RARA fusion;PP8675;probable transcription factor PML;promyelocytic leukemia protein;promyelocytic leukemia, inducer of;protein PML;RING finger protein 71;RING-type E3 SUMO transferase PML;RNF71;TRIM19;tripartite motif protein TRIM19;tripartite motif-containing protein 19
- Extra Details:
- PML is a transcription factor and tumor suppressor which belongs to the tripartite motif (TRIM) family. This motif contains three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. PML regulates the response of p53 to oncogenic signals. It is often involved in a chromosomal translocation between chromosomes 15 and 17 which results in a PML/RARalpha fusion protein and is associated with most cases of acute promyelocytic leukemia. Anti-PML Antibody is ideal for research in Gene Expression, Cell Cycle Control and Cancer.
- Shipping Conditions:
- Dry Ice