ITGA3 Antibody

Cannot supply to this region.

SKU:: 600-401-R13
Additional Names:: CD49 antigen-like family member C,FRP-2,Galactoprotein B3,|ITGA3
Application:: Flow Cytometry, IHC, WB, IF
Concentration:: 0.5 mg/ml
Physical State:: Lyophilized
Species Reactivity:: Human
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3
Immunogen:: ITGA3 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the N-terminal of human ITGA3.
Formulation:: 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3
Uniprot:: P26006
Synonyms:: alpha 3 subunit of VLA-3 receptor;antigen CD49C;antigen identified by monoclonal antibody J143;CD49 antigen-like family member C;CD49C;FRP-2;galactoprotein B3;GAP-B3;GAPB3;ILNEB;integrin alpha 3;integrin alpha-3;integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor);MSK18;testicular tissue protein Li 96;testicular tissue protein Li 98;VCA-2;very late activation protein 3 receptor, alpha-3 subunit;VL3A;VLA-3 subunit alpha;VLA3a
Extra Details:: ITGA3(INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis. This antibody is suitable for researchers interested in cancer research.

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