PLAUR Antibody

Cannot supply to this region.

SKU:: 600-401-P91
Additional Names:: Monocyte activation antigen Mo3,CD_antigen=CD87,|PLAUR
Application:: IHC, WB
Concentration:: 0.5 mg/ml
Physical State:: Lyophilized
Species Reactivity:: Human
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3
Immunogen:: PLAUR affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human PLAUR.
Formulation:: 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3
Uniprot:: Q03405
Synonyms:: CD87;monocyte activation antigen Mo3;U-PAR;u-plasminogen activator receptor form 2;UPAR;URKR;urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor
Extra Details:: PLAUR(PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase. This antibody is suitable for researchers interested in neuroscience research.

Shipping Conditions:: Ambient