TLR4 Antibody

Cannot supply to this region.

SKU:: 600-401-MK3S
Additional Names:: Rabbit Anti-TLR4 Antibody, ARMD10 antibody, CD284 antibody, Toll (Drosophila) homolog antibody, HToll, Homolog of Drosophila Toll, TLR-4 Antibody, TOLL antibody, Toll Endotoxin Hyporesponsiveness antibody, Toll like receptor 4 antibody, Toll like receptor 4 precursor antibody|TLR4
Application:: ELISA, IHC, WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C diluted. Avoid freeze/thaw cycles., See Manual Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the n-terminus of human TLR4 protein.
Formulation:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Uniprot:: O00206
Synonyms:: ARMD10;CD284;homolog of Drosophila toll;hToll;TLR-4;TOLL;toll like receptor 4 protein;toll-like receptor 4
Extra Details:: TLR4 (Toll-Like Receptor 4). Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis. Mutations in this gene have been associated with differences in LPS responsiveness, macular degeneration, and pertussis. Anti-TLR4 Antibody is useful for researchers interested in transcription factor research, cytokine research, MIF action through Endocytic Pathway, and rheumatoid arthritis.

Shipping Conditions:: Dry Ice