600-401-J74
HDAC9 (internal) Antibody
Cannot supply to this region.
- SKU:
- 600-401-J74
- Additional Names:
- HDAC9|rabbit anti-HDAC-9 antibody, HDAC9, HDAC 9, HD-9, HD 9, Histone deacetylase 9, Histone deacetylase-9, HD9, Histone deacetylase 7B, HD7, HD7b, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, HDAC7, HDAC7B, HDRP, MITR
- Application:
- ELISA, IHC, WB
- Concentration:
- 1.1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-HDAC9 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human HDAC9 protein.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9UKV0
- Synonyms:
- HD7;HD7b;HD9;HDAC;HDAC7;HDAC7B;HDAC9B;HDAC9FL;HDRP;histone deacetylase 4/5-related protein;histone deacetylase 7B;histone deacetylase 9;Histone deacetylase-related protein;MEF-2 interacting transcription repressor (MITR) protein;MEF2-interacting transcription repressor MITR;MITR
- Extra Details:
- HDAC9 is located in the nucleus, expressed most highly in brain, heart, muscle, and testis. It is responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). The result of deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC9 represses MEF2-dependent transcription by recruiting HDAC1 and 3. It appears to inhibit skeletal myogenesis and be a factor in heart development. By repressing JUN transcription via HDAC1 and inhibiting JUN phosphorylation by MAPK10, HDAC9 protects neurons from apoptosis. Anti-HDAC9 therefore is ideal for investigators interested in Cardiovascular or Epigenetics and Nuclear Signaling research.
- Shipping Conditions:
- Dry Ice