ST2 Antibody

Cannot supply to this region.

SKU:: 600-401-H20
Additional Names:: Il1rl1|Ly84, St2, Ste2, Interleukin-1 receptor-like 1, Interleukin-33 receptor alpha chain1, Lymphocyte antigen 84, Protein ST2, Protein T1
Application:: ELISA, IHC, WB, IF
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Mouse
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:: ST2 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to amino acids at the n-terminus of mouse ST2. This peptide is common to all three known ST2 isoforms.
Formulation:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Uniprot:: P14719
Synonyms:: DER;DER4;Fit-;Fit-1;interleukin-1 receptor-like 1;interleukin-33 receptor alpha chain;Ly8;Ly84;lymphocyte antigen 84;Protein ST2;Protein T1;ST;St2;St2-;St2-rs1;ST2L;T1;T1/ST;T1/ST2
Extra Details:: ST2 antibody detects mouse ST2 and is common to all three isoforms. ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP. Anti-ST2 antibodies are ideal for investigators involved in cytokine and growth factors research.

Shipping Conditions:: Dry Ice