600-401-GF1
ZIP6 Antibody
Cannot supply to this region.
- SKU:
- 600-401-GF1
- Additional Names:
- SLC39A6|ZIP6 Antibody, LIV-1, LIV1, ZIP6, Zinc transporter ZIP6, Estrogen-regulated protein LIV-1, ZIP-6
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-ZIP6 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the internal region of human ZIP6.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q13433
- Synonyms:
- estrogen-regulated protein LIV-1;LIV-1;LIV-1 protein, estrogen regulated;LIV1;solute carrier family 39 (metal ion transporter), member 6;solute carrier family 39 (zinc transporter), member 6;Solute carrier family 39 member 6;zinc transporter ZIP6;ZIP-6;ZIP6;zrt- and Irt-like protein 6
- Extra Details:
- The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.
- Shipping Conditions:
- Blue Ice