600-401-GD0
ZEB1 Antibody
Cannot supply to this region.
- SKU:
- 600-401-GD0
- Additional Names:
- ZEB1|ZEB1 Antibody, BZP, TCF8, AREB6, FECD6, NIL2A, PPCD3, ZFHEP, ZFHX1A, DELTAEF1, Zinc finger E-box-binding homeobox 1, NIL-2-A zinc finger protein, TCF-8
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-ZEB1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the internal region of human ZEB1.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P37275
- Synonyms:
- AREB6;BZP;delta-crystallin enhancer binding factor 1;DELTAEF1;FECD6;negative regulator of IL2;NIL-2-A zinc finger protein;NIL2A;posterior polymorphous corneal dystrophy 3;PPCD3;TCF8;Transcription factor 8;transcription factor 8 (represses interleukin 2 expression);ZFHEP;ZFHX1A;zinc finger E-box-binding homeobox 1;zinc finger homeodomain enhancer-binding protein
- Extra Details:
- ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in post gastrulation embryogenesis. ZEB1 binds to the promoter of several hemopoietic genes, including interleukin-2, CD4, GATA-3, and alpha-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy.
- Shipping Conditions:
- Blue Ice