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DEDAF Antibody

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  2. Polyclonal

600-401-G95

DEDAF Antibody

Cannot supply to this region.

SKU:
600-401-G95
Additional Names:
RING1 and YY1-binding protein, Apoptin-associating protein 1, APAP-1, Death effector domain-associated factor, DED-associated factor, YY1 and E4TF1-associated factor 1, RYBP, DEDAF, YEAF1|RYBP
Application:
ELISA, IHC, WB, IF
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Storage Conditions:
2-8[o]C
Supplier:
Rockland Inc
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:
DEDAF Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to an internal region of human DEDAF. The sequence is identical to that of mouse origin.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Uniprot:
Q8N488
Synonyms:
AAP1;APAP-1;apoptin-associating protein 1;death effector domain-associated factor;DED-associated factor;DEDAF;RING1 and YY1-binding protein;ring1 interactor RYBP;YEAF1;YY1 and E4TF1 associated factor 1;YY1 and E4TF1-associated factor 1
Extra Details:
DEDAF antibody detects human DEDAF. Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. Several molecules including caspases and adaptor FADD contain DEDs. A novel protein that interacts with DED of caspase-8 and 10, and FADD was identified recently and designated DEDAF for DED associated factor. DEDAF is identical to the transcriptional repressor RYBP. DEDAF/RYBP is expressed in multiple tissues and cell lines. DEDAF interacts with FADD and augments the formation of CD95/FADD/capase-8 complexes at the cell membrane, and interacts with DED-containing DNA biding protein (DEDD) in the nucleus indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis. Anti-DEDAF antibodies are ideal for investigators involved in Apoptosis and NFkappaB research.
Shipping Conditions:
Blue Ice