600-401-FW0
VARP Antibody
Cannot supply to this region.
- SKU:
- 600-401-FW0
- Additional Names:
- ANKRD27|VARP Antibody, VARP, PP12899, Ankyrin repeat domain-containing protein 27, VPS9 domain-containing protein
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-VARP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the N-terminus of human VARP.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q96NW4
- Synonyms:
- ankyrin repeat domain 27 (VPS9 domain);ankyrin repeat domain-containing protein 27;PP12899;VARP;Vps9 domain and ankyrin-repeat-containing protein;VPS9 domain-containing protein;VPS9-ankyrin-repeat protein
- Extra Details:
- The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.
- Shipping Conditions:
- Dry Ice