600-401-FT6
UBC13 Antibody
Cannot supply to this region.
- SKU:
- 600-401-FT6
- Additional Names:
- UBC13 Antibody, UBC13, UbcH13, HEL-S-71, UbcH-ben, BLU, Ubiquitin-conjugating enzyme E2 N, Bendless-like ubiquitin-conjugating enzyme|UBE2N
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-UBC13 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 15 amino acids near the C-terminus of human UBC13.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P61088
- Synonyms:
- bendless-like ubiquitin conjugating enzyme;Bendless-like ubiquitin-conjugating enzyme;E2 ubiquitin-conjugating enzyme N;epididymis secretory protein Li 71;HEL-S-71;UBC13;UbcH-ben;UbcH13;UBCHBEN; UBC13;ubiquitin carrier protein N;ubiquitin conjugating enzyme E2N;ubiquitin-conjugating enzyme E2 N;ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13);ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast);ubiquitin-protein ligase N;yeast UBC13 homolog
- Extra Details:
- Ubiquitin-conjugating enzyme 13 (Ubc13) was initially discovered in S. cerevisiae as a DNA-damage inducible protein involved in the error-free DNA postreplication repair pathway. It has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway. Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors. Ubc13 is part of a dimeric ubiquitin-conjugating enzyme complex also containing UEV1A (ubiquitin-conjugating enzyme E2 variant 1) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase kinase kinase family. The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation.
- Shipping Conditions:
- Dry Ice