600-401-FS9
TWEAK Antibody
Cannot supply to this region.
- SKU:
- 600-401-FS9
- Additional Names:
- TNFSF12|TWEAK Antibody, APO3L, DR3LG, TWEAK, APO3L, UNQ181/PRO207, Tumor necrosis factor ligand superfamily member 12, APO3 ligand
- Application:
- ELISA, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-TWEAK antibody was prepared from whole rabbit serum produced by repeated immunizations with recombinant human TWEAK.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- O43508
- Synonyms:
- APO3 ligand;APO3/DR3 ligand;APO3L;DR3LG;TNF-related WEAK inducer of apoptosis;TNFSF12-TNFSF13 protein;TNLG4A;tumor necrosis factor (ligand) superfamily, member 12;tumor necrosis factor (ligand) superfamily, member 12-member 13;tumor necrosis factor ligand 4A;tumor necrosis factor ligand superfamily member 12;tumor necrosis factor superfamily member 12;TWE-PRIL;TWEAK
- Extra Details:
- TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.
- Shipping Conditions:
- Dry Ice