600-401-FP2
TRIM28 Antibody
Cannot supply to this region.
- SKU:
- 600-401-FP2
- Additional Names:
- TRIM28|TRIM28 Antibody, KAP1, TF1B, RNF96, TIF1B, KAP1, Transcription intermediary factor 1-beta, E3 SUMO-protein ligase TRIM28, TIF1-beta
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-TRIM28 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid peptide near the C-terminus of human TRIM28.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q13263
- Synonyms:
- E3 SUMO-protein ligase TRIM28;KAP-1;KAP1;KRAB [Kruppel-associated box domain]-associated protein 1;KRAB-associated protein 1;KRAB-interacting protein 1;KRIP-1;nuclear corepressor KAP-1;PPP1R157;protein phosphatase 1, regulatory subunit 157;RING finger protein 96;RING-type E3 ubiquitin transferase TIF1-beta;RNF96;TF1B;TIF1-beta;TIF1B;transcription intermediary factor 1-beta;transcriptional intermediary factor 1-beta;Tripartite motif-containing protein 28
- Extra Details:
- TRIM28, also known as KAP-1, is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily and contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TRIM28 is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TRIM28 acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TRIM28 associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation.
- Shipping Conditions:
- Dry Ice