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TCCR Antibody

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  2. Polyclonal

600-401-FA3

TCCR Antibody

Cannot supply to this region.

SKU:
600-401-FA3
Additional Names:
Interleukin-27 receptor subunit alpha, IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, IL-27RA, Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor, TCCR, ZcytoR1, IL27RA, CRL1, TCCR, WSX1, UNQ296/PRO336|TCCR
Application:
ELISA, IHC, WB, IF
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Host:
Rabbit
Reactivities:
Human
Buffer:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
Immunogen:
Anti-TCCR antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the C-terminus of human TCCR precursor. This sequence is identical to that of mouse TCCR.
Formulation:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Uniprot:
Q6UWB1
Synonyms:
class I cytokine receptor;CRL1;cytokine receptor WSX-1;cytokine receptor-like 1;IL-27 receptor subunit alpha;IL-27R subunit alpha;IL-27R-alpha;IL-27RA;IL27R;interleukin 27 receptor, alpha;interleukin-27 receptor subunit alpha;T-cell cytokine receptor type 1;TCCR;type I T-cell cytokine receptor;WSX1;zcytor1
Extra Details:
Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.
Shipping Conditions:
Dry Ice